“It is with great pleasure that I share with you our 2018 Activity Report, which reflects the progress we have made in addressing Gram-negative drug-resistant infections in children, newborns with sepsis, and sexually-transmitted infections.”
[Geneva – 23 May 2019]
DNDi and GARDP welcome the adoption of the resolution on AMR and call for continued political commitment at the highest level, including at the UN High-Level Meeting on Universal Health Coverage at the UN General Assembly in September.
19 February 2019
GARDP’s response focuses on R&D for human health, while recognizing and supporting the need for better prevention of infections in humans and animals, a One Health approach, and the potential for synergies between approaches taken.
“2018 has been a landmark year for GARDP. We have made significant progress to address important global health priorities such as drug-resistant infections in children, newborns with sepsis, and sexually-transmitted infections. None of this would have been possible without your support.”
GARDP recently announced a new partnership with Novartis to reduce child deaths from drug-resistant infections, and kicked of a study in newborns with sepsis to guide development of new treatments to reverse global increase in their deaths. Listen to Dr Manica Balasegaram, GARDP’s Executive Director talk about what inspired him to create GARDP. Register for upcoming webinars on antimicrobial drug development and catch-up on those you may have missed.
“I am pleased to share with you GARDP’s 2017 Activity Report, which reflects our contribution to developing and delivering new and improved antibiotic treatments that address global public health need while endeavouring to ensure their sustainable access.”
The neonatal sepsis programme was launched in 2017 with two target product profiles to guide development of improved antibiotic treatment for drug-resistant sepsis in babies. GARDP’s first partnership agreement was signed with Entasis Therapeutics to co-develop zoliflodacin, a novel first-in-class oral antibiotic to address the rapidly growing threat of drug-resistant gonorrhoea. GARDP has also developed a programme to recover and share experts´ knowledge to speed up antibiotic drug discovery and build a long-term portfolio.
“The year 2017 was an extraordinary first full year of activity for GARDP. Thanks to you, we are now ending the year as an established R&D partnership with three R&D programmes launched, an independent Scientific Advisory Committee, a seven-year business plan, a liaison office in Cape Town, South Africa, and an additional EUR 56.5 million in newly raised funds.”
On 4th September 2017, Germany together with a number of countries, pledged EUR 56.5 million during a fundraising event for GARDP hosted in Berlin by the German Federal Ministry of Health and the German Federal Ministry of Education and Research. Contributions were made by the Netherlands, Switzerland, South Africa, the Wellcome Trust, Luxembourg, the United Kingdom and Germany. This is an important step for GARDP in order to support the implementation of GARDP’s business plan and its R&D programmes. Learn more about the pledging event: gardp.org/pledging
GARDP has finalized its first seven-year business plan, which outlines the overall R&D strategy, prioritization process, and sustainable access approach, and notably serves as a roadmap for its concrete R&D programmes for the coming years. An official Scientific Advisory Committee (SAC) has now been approved by the DNDi Board of Directors (GARDP’s governing body). This committee of experts in drug-resistant infections and in drug discovery and development advises on GARDP programmes and projects.
GARDP has, within its first 8 months, built up a team of 10 people with additional support staff from DNDi contributing directly to GARDP programmes.